We are also investigating how this same senescent state occurs during early cancer formation as an anti-cancer therapeutic target. We have described how these cells enter a state of shock, named senescence, in response to injury, and how preventing them from doing so can promote liver regeneration. These cells show immense regenerative capacity but are also the principle source of the most common primary liver cancer, hepatocellular carcinoma (HCC). But while bird flu has killed hundreds of millions of birds globally, it has sickened fewer than 900 people since 2003 and has not been able to spread easily among humans.My group has been interested in studying the regenerative responses to injury and aberrant proliferative responses in cancer of hepatocytes, the principle functional cell of the liver. Scientists worry that rising cases of H5N1, particularly in animals that have frequent contact with humans, might lead to a mutated version of the disease that could spread easily between people, triggering another pandemic.īefore the COVID-19 pandemic, many experts had suspected that the next global outbreak would be sparked by H5N1. Since 2020, WHO said a dozen human cases have been reported. Testing last week found that 29 had H5N1.Īs of June, the most recent variant of H5N1 has been reported in birds and other animal species in Asia, Africa, Europe and the Americas. WHO said that late last month, Polish authorities informed agency officials of the unusual deaths of more than 45 cats in 13 geographical regions of the country. health agency said it was the first time so many cats had been reported to have bird flu over such a wide geographical area in a single country, amid an unprecedented global outbreak of the latest version of the H5N1 version of the disease. LONDON (AP) - The World Health Organization said more than two dozen cats have been infected with bird flu across Poland, but no people appeared to have been sickened.
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